Multidrug Resistance


Huge amounts of antibiotics are being used around the globe for human therapies, growing farm animals and even in aquaculture, resulting in the selection of pathogenic bacteria resistant to multiple drugs. Multidrug resistance in microbes may be generated by one of two mechanisms. First, these microbes may accumulate multiple genes, each coding for resistance to a single drug, within a single cell. This accumulation occurs typically on resistance (R) plasmids. Second, multidrug resistance may also occur by the increased expression of genes that code for multidrug efflux pumps, extruding a wide range of drugs. This conference discusses our existing knowledge on the molecular mechanisms involved in multiple types of resistances offered by these microbes. An even more serious threat may be the emergence of gram-negative pathogens that are resistant to essentially all of the available agents. Researchers had time to react against the threat by MRSA. Thus, there are newly developed agents that are active against vancomycin-resistant MRSA, such as linezolid and quinupristin/dalfopristin. However, the emergence of “pan-resistant” gram-negative strains, notably those belonging to the family of Pseudomonas aeruginosa and Acinetobacter baumanii, occurred more recently, after most major pharmaceutical companies stopped the development of new antibacterial agents. The time will not be far where we will be running out of compounds used to treat basic diseases.

Subtracks

  1. Mutational Alteration of the Target Protein
  2. Enzymatic Inactivation of the Drug
  3. Acquisition of Genes for Less Susceptible Target Proteins from Other Species
  4. Bypassing of the Target

    Related Conference of Multidrug Resistance

    April 12-13, 2021

    2nd International Conference on Biosimilars & Pharmaceuticals

    Auckland, Newzealand
    April 28-29, 2021

    31st Annual European Pharma Congress

    London, UK
    April 28-29, 2021

    14th European Biosimilars Congress

    London, UK
    May 10-11, 2021

    20th Annual Meet on Pharmaceutical Sciences

    Yokohama, Japan
    May 12-12, 2021

    27th Cognitive Neuroscience Congress

    London, UK
    May 17-17, 2021

    Annual Meet on Pharmacovigilance & Drug Safety

    Tokyo, Japan
    May 17-18, 2021

    8th European Biopharma Congress

    Prague, Czech Republic
    May 17-18, 2021

    24th Asia Pacific Pharma Congress

    Melbourne, Australia
    June 07-08, 2021

    2nd European Conference on Pharmacovigilance and Drug Safety

    Prague, Czech Republic
    June 21-22, 2021

    1 st Global Summit on Generic Drugs and Quality Control

    Prague, Czech Republic
    July 06-07, 2021

    14th Global Pharmacovigilance And Clinical Trials Summit

    Albufeira, Portugal
    July 10-11, 2021

    2 nd Pharma Expo China

    Tokyo, Japan
    July 26-27, 2021

    36th World Pharmacology and Therapeutics Forum

    Paris, France
    July 30-30, 2021

    12th World Congress on Bioavailability and Bioequivalence

    Prague, Czech Republic
    August 16-17, 2021

    Global summit on Cosmetic & Reconstructive Surgery

    Tokyo, Japan
    August 16-17, 2021

    34rd World Congress on Pharmacology

    London, UK
    August 23-24, 2021

    7th World Congress on Medicinal Plants and Marine Drugs

    Prague, Czech Republic
    August 30-31, 2021

    20th Medicinal & PharmaceuticalSciences Congress

    London, UK
    September 13-14, 2021

    3rd World Congress on Drug Discovery and Drug Design

    Tokyo, Japan
    September 17-18, 2021

    9th International Conference on Clinical Trials

    Montreal, Canada
    September 20-21, 2021

    Asia Pacific Pharmaceutics & Drug Delivery Congress

    Tokyo, Japan
    September 27-28, 2021

    2 nd World Pharma Expo

    Tokyo, Japan
    October 05-06, 2021

    International Congress on Drug Delivery

    Auckland, Newzealand
    October 21-22, 2021

    2nd Annual Congress on Antibiotics and Bacterial Infections

    Geneva, Switzerland
    October 29-30, 2021

    14th World Drug Delivery Summit

    Vancouver, Canada
    October 29-30, 2021

    12th Annual Biomarkers and Clinical Research Congress

    Vancouver, Canada
    November 16-17, 2021

    World Congress on Biologics and Biosimilars

    Osaka, Japan
    November 26-27, 2021

    World Biosimilars & Biologics Congress

    Vancouver, Canada
    December 02-03, 2021

    17th Annual Congress on Pharmacology and Toxicology

    Tokyo, Japan
    December 02-03, 2021

    International Conference on Bio Pharmaceutics

    Auckland, Newzealand
    December 07-08, 2021

    2nd International Conference on Biotechnology and Healthcare

    Auckland, Newzealand
    December 15-16, 2021

    12th World Congress on Bioavailability and Bioequivalence

    Bali, Indonesia

    Multidrug Resistance Conference Speakers

    Recommended Sessions

    Related Journals

    Are you interested in