Multidrug Resistance


Huge amounts of antibiotics are being used around the globe for human therapies, growing farm animals and even in aquaculture, resulting in the selection of pathogenic bacteria resistant to multiple drugs. Multidrug resistance in microbes may be generated by one of two mechanisms. First, these microbes may accumulate multiple genes, each coding for resistance to a single drug, within a single cell. This accumulation occurs typically on resistance (R) plasmids. Second, multidrug resistance may also occur by the increased expression of genes that code for multidrug efflux pumps, extruding a wide range of drugs. This conference discusses our existing knowledge on the molecular mechanisms involved in multiple types of resistances offered by these microbes. An even more serious threat may be the emergence of gram-negative pathogens that are resistant to essentially all of the available agents. Researchers had time to react against the threat by MRSA. Thus, there are newly developed agents that are active against vancomycin-resistant MRSA, such as linezolid and quinupristin/dalfopristin. However, the emergence of “pan-resistant” gram-negative strains, notably those belonging to the family of Pseudomonas aeruginosa and Acinetobacter baumanii, occurred more recently, after most major pharmaceutical companies stopped the development of new antibacterial agents. The time will not be far where we will be running out of compounds used to treat basic diseases.

Subtracks

  1. Mutational Alteration of the Target Protein
  2. Enzymatic Inactivation of the Drug
  3. Acquisition of Genes for Less Susceptible Target Proteins from Other Species
  4. Bypassing of the Target

    Related Conference of Multidrug Resistance

    February 24-25, 2025

    2nd International Conference on Pharmacognosy

    Madrid, Spain
    February 27-28, 2025

    8th International on Pharmacy and Pharmaceutical Conference

    Prague, Czech Republic
    March 10-11, 2025

    35th Annual European Pharma Congress

    Rome, Italy
    April 14-15, 2025

    18th European Biosimilars Congress

    Paris, France
    April 24-25, 2025

    18th World Drug Delivery Summit

    London, UK
    May 05-06, 2025

    19th World Drug Delivery Summit

    Vancouver, Canada
    June 16-17, 2025

    3rd Global Online Summit on Nanoscience and Nanotechnology

    Zurich, Switzerland
    June 23-24, 2025

    38th World Congress on Pharmacology

    Aix-en-Provence, France
    September 23-24, 2025

    10th International Conference on Future Pharma and Innovations

    Amsterdam, Netherlands
    November 27-28, 2025

    4th World Conference on Pharma Industry and Medical Devices

    Zurich, Switzerland
    November 27-28, 2025

    4th World Congress on Precision and Personalized Medicine

    Zurich, Switzerland

    Multidrug Resistance Conference Speakers

      Recommended Sessions

      Related Journals

      Are you interested in